Dr. Sarah Höhn

Researchgate Profile: Sarah Höhn

PhD:

Influence of nanostructured surfaces on corrosion behavior and bioactivity of TiAl6V4 under adjusted in-vitro experimental conditions

In this project the influence of different nanostructured coatings on corrosion behavior and deposition of calcium phosphates is investigated under long-term immersion tests. Organic, inorganic and polymeric coatings on TiAl6V4 are immersed in cell culture medium under physilogical and simulated inflammatory conditions. After different immersion times the surfaces are characterized by means of SEM, XPS, EIS and ToF-SIMS. Cytotoxicity, cell proliferation and mineral phases are investigated by means of stem cells and osteogenic induction.

PostDoc:

Protein adsorption on flat glass surfaces – characterisation of quartz glass, soda lime, borosilicate glass, and bioactive glass (45S5) after protein adsorption at different pH values and pretreatments of the surface.

The research deals with the interactions of proteins with biomaterial surfaces, including metallic and non-metallic materials. The effect of surface charge, composition, surface chemistry, as well as pH of the solution will be investigated and the protein adhesion to the surface will be analyzed. This project is carried out in close collaboration with Prof. Dr.-Ing. habil. Aldo R. Boccaccini (Institute of Biomaterials, WW7).